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Study protocol: design and rationale for an exploratory phase II randomized controlled trial to determine optimal vitamin D(3) supplementation strategies for acute fracture healing

BACKGROUND: Observational studies have found that 75% of healthy adult fracture patients (ages 18–50) have serum 25-hydroxyvitamin D (25(OH)D) levels < 30 ng/mL. Although lower serum 25(OH)D levels have yet to be correlated to fracture healing complications or poor fracture outcomes, many orthope...

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Detalles Bibliográficos
Autores principales: Sprague, Sheila, Bzovsky, Sofia, Connelly, Daniel, Thabane, Lehana, Adachi, Jonathan D., Slobogean, Gerard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873563/
https://www.ncbi.nlm.nih.gov/pubmed/31768262
http://dx.doi.org/10.1186/s40814-019-0524-4