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Solid-Supported Proteins in the Liquid Chromatography Domain to Probe Ligand-Target Interactions

Ligand-target interactions play a central role in drug discovery processes because these interactions are crucial in biological systems. Small molecules-proteins interactions can regulate and modulate protein function and activity through conformational changes. Therefore, bioanalytical tools to scr...

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Detalles Bibliográficos
Autores principales: de Moraes, Marcela Cristina, Cardoso, Carmen Lucia, Cass, Quezia Bezerra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873629/
https://www.ncbi.nlm.nih.gov/pubmed/31803714
http://dx.doi.org/10.3389/fchem.2019.00752