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Solid-Supported Proteins in the Liquid Chromatography Domain to Probe Ligand-Target Interactions
Ligand-target interactions play a central role in drug discovery processes because these interactions are crucial in biological systems. Small molecules-proteins interactions can regulate and modulate protein function and activity through conformational changes. Therefore, bioanalytical tools to scr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873629/ https://www.ncbi.nlm.nih.gov/pubmed/31803714 http://dx.doi.org/10.3389/fchem.2019.00752 |