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ImaGene: a convolutional neural network to quantify natural selection from genomic data

BACKGROUND: The genetic bases of many complex phenotypes are still largely unknown, mostly due to the polygenic nature of the traits and the small effect of each associated mutation. An alternative approach to classic association studies to determining such genetic bases is an evolutionary framework...

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Detalles Bibliográficos
Autores principales: Torada, Luis, Lorenzon, Lucrezia, Beddis, Alice, Isildak, Ulas, Pattini, Linda, Mathieson, Sara, Fumagalli, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873651/
https://www.ncbi.nlm.nih.gov/pubmed/31757205
http://dx.doi.org/10.1186/s12859-019-2927-x