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The new complement inhibitor CRIg/FH ameliorates lupus nephritis in lupus-prone MRL/lpr mice

BACKGROUNDS: The aberrant activation of complement system is critically involved in lupus nephropathy. Recent study showed complement C3 inhibitor was effective in the treatment of lupus nephropathy. In this study, we investigate the effect of a novel complement C3 inhibitor, CRIg/FH, in the treatme...

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Detalles Bibliográficos
Autores principales: Shi, Yu, Yao, Wen, Sun, Li, Li, Guomin, Liu, Haimei, Ding, Peipei, Hu, Weiguo, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873683/
https://www.ncbi.nlm.nih.gov/pubmed/31752725
http://dx.doi.org/10.1186/s12882-019-1599-0