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Distinct functions of AKT isoforms in breast cancer: a comprehensive review
BACKGROUND: AKT, also known as protein kinase B, is a key element of the PI3K/AKT signaling pathway. Moreover, AKT regulates the hallmarks of cancer, e.g. tumor growth, survival and invasiveness of tumor cells. After AKT was discovered in the early 1990s, further studies revealed that there are thre...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873690/ https://www.ncbi.nlm.nih.gov/pubmed/31752925 http://dx.doi.org/10.1186/s12964-019-0450-3 |