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Leveraging Single-Cell RNA Sequencing Experiments to Model Intratumor Heterogeneity
PURPOSE: Many cancers can be treated with targeted therapy. Almost inevitably, tumors develop resistance to targeted therapy, either from pre-existence or by evolving new genotypes and traits. Intratumor heterogeneity serves as a reservoir for resistance, which often occurs as a result of the select...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Clinical Oncology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873939/ https://www.ncbi.nlm.nih.gov/pubmed/30995123 http://dx.doi.org/10.1200/CCI.18.00074 |