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SUR-8 interacts with PP1-87B to stabilize PERIOD and regulate circadian rhythms in Drosophila
Circadian rhythms are generated by endogenous pacemakers that rely on transcriptional-translational feedback mechanisms conserved among species. In Drosophila, the stability of a key pacemaker protein PERIOD (PER) is tightly controlled by changes in phosphorylation status. A number of molecular play...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874087/ https://www.ncbi.nlm.nih.gov/pubmed/31710605 http://dx.doi.org/10.1371/journal.pgen.1008475 |