PDHA1 Gene Knockout In Human Esophageal Squamous Cancer Cells Resulted In Greater Warburg Effect And Aggressive Features In Vitro And In Vivo

BACKGROUND: One of the remarkable metabolic characteristics of cancer cells is that they prefer glycolysis rather than oxidative phosphorylation (OXPHOS). Pyruvate dehydrogenase E1 alpha subunit (PDHA1) is an important prerequisite for OXPHOS. Our previous studies have shown that low level of PDHA1...

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Detalles Bibliográficos
Autores principales: Liu, Lan, Cao, Jing, Zhao, Jing, Li, Xiangyu, Suo, Zhenhe, Li, Huixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874154/
https://www.ncbi.nlm.nih.gov/pubmed/31819487
http://dx.doi.org/10.2147/OTT.S226851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874154/
https://www.ncbi.nlm.nih.gov/pubmed/31819487
http://dx.doi.org/10.2147/OTT.S226851

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