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Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain

Peripheral and central neurons in the pain pathway are well equipped to detect and respond to extracellular stimuli such as pro-inflammatory mediators and neurotransmitters through the cell surface expression of receptors that can mediate rapid intracellular signaling. Following injury or infection,...

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Detalles Bibliográficos
Autores principales: Retamal, Jeffri S., Ramírez-García, Paulina D., Shenoy, Priyank A., Poole, Daniel P., Veldhuis, Nicholas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874167/
https://www.ncbi.nlm.nih.gov/pubmed/31798411
http://dx.doi.org/10.3389/fnmol.2019.00273