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Chromatin Environment and Cellular Context Specify Compensatory Activity of Paralogous MEF2 Transcription Factors

Compensation among paralogous transcription factors (TFs) confers genetic robustness of cellular processes, but how TFs dynamically respond to paralog depletion on a genome-wide scale in vivo remains incompletely understood. Using single and double conditional knockout of myocyte enhancer factor 2 (...

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Detalles Bibliográficos
Autores principales: Majidi, Shahriyar P., Reddy, Naveen C., Moore, Michael J., Chen, Hao, Yamada, Tomoko, Andzelm, Milena M., Cherry, Timothy J., Hu, Linda S., Greenberg, Michael E., Bonni, Azad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874310/
https://www.ncbi.nlm.nih.gov/pubmed/31722213
http://dx.doi.org/10.1016/j.celrep.2019.10.033