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Increased amounts and stability of telomeric repeat-containing RNA (TERRA) following DNA damage induced by etoposide
Telomeric repeat-containing RNAs (TERRAs) are long noncoding RNAs transcribed from subtelomeres toward telomeric repeat tracts, which have been implicated in telomere protection and heterochromatin formation. Genotoxic stress leads to upregulation of TERRAs. However, the mechanism of DNA damage-medi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874320/ https://www.ncbi.nlm.nih.gov/pubmed/31756221 http://dx.doi.org/10.1371/journal.pone.0225302 |