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Surveillance to maintain the sensitivity of genotype-based antibiotic resistance diagnostics

The sensitivity of genotype-based diagnostics that predict antimicrobial susceptibility is limited by the extent to which they detect genes and alleles that lead to resistance. As novel resistance variants are expected to emerge, such sensitivity is expected to decline unless the new variants are de...

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Detalles Bibliográficos
Autores principales: Hicks, Allison L., Kissler, Stephen M., Lipsitch, Marc, Grad, Yonatan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874359/
https://www.ncbi.nlm.nih.gov/pubmed/31714937
http://dx.doi.org/10.1371/journal.pbio.3000547