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Surveillance to maintain the sensitivity of genotype-based antibiotic resistance diagnostics
The sensitivity of genotype-based diagnostics that predict antimicrobial susceptibility is limited by the extent to which they detect genes and alleles that lead to resistance. As novel resistance variants are expected to emerge, such sensitivity is expected to decline unless the new variants are de...
Autores principales: | Hicks, Allison L., Kissler, Stephen M., Lipsitch, Marc, Grad, Yonatan H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874359/ https://www.ncbi.nlm.nih.gov/pubmed/31714937 http://dx.doi.org/10.1371/journal.pbio.3000547 |
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