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Neuroprotective effects of protocatechuic aldehyde through PLK2/p-GSK3β/Nrf2 signaling pathway in both in vivo and in vitro models of Parkinson's disease

Mitochondrial dysfunction and oxidative damage are closely related to the pathogenesis of Parkinson's disease (PD). The pharmacological mechanism of protocatechuic aldehyde (PCA) for PD treatment have retained unclear. The purposes of the present study were to clarify the neuroprotective effect...

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Detalles Bibliográficos
Autores principales: Guo, Chao, Zhu, Junrong, Wang, Jingwen, Duan, Jialin, Ma, Shanbo, Yin, Ying, Quan, Wei, Zhang, Wei, Guan, Yue, Ding, Yi, Wen, Aidong, Zhang, Yingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874433/
https://www.ncbi.nlm.nih.gov/pubmed/31697645
http://dx.doi.org/10.18632/aging.102394