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Neuroprotective effects of protocatechuic aldehyde through PLK2/p-GSK3β/Nrf2 signaling pathway in both in vivo and in vitro models of Parkinson's disease
Mitochondrial dysfunction and oxidative damage are closely related to the pathogenesis of Parkinson's disease (PD). The pharmacological mechanism of protocatechuic aldehyde (PCA) for PD treatment have retained unclear. The purposes of the present study were to clarify the neuroprotective effect...
Autores principales: | Guo, Chao, Zhu, Junrong, Wang, Jingwen, Duan, Jialin, Ma, Shanbo, Yin, Ying, Quan, Wei, Zhang, Wei, Guan, Yue, Ding, Yi, Wen, Aidong, Zhang, Yingdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874433/ https://www.ncbi.nlm.nih.gov/pubmed/31697645 http://dx.doi.org/10.18632/aging.102394 |
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