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Age-associated changes in human CD4(+) T cells point to mitochondrial dysfunction consequent to impaired autophagy
To gain understanding on the mechanisms that drive immunosenescence in humans, we examined CD4(+) T cells obtained from younger (20-39 years-old) and older (70+ years-old) healthy participants of the Baltimore Longitudinal Study on Aging (BLSA). We found that mitochondrial proteins involved in the e...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874450/ https://www.ncbi.nlm.nih.gov/pubmed/31707363 http://dx.doi.org/10.18632/aging.102438 |