Oncogenic USP22 supports gastric cancer growth and metastasis by activating c-Myc/NAMPT/SIRT1-dependent FOXO1 and YAP signaling

In this study, we investigated the role of ubiquitin-specific protease 22 (USP22) in the growth and progression of gastric cancer (GC). USP22 mRNA and protein levels were significantly higher in GC tissue samples and GC cell lines than in adjacent noncancerous tissue samples and a normal gastric muc...

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Detalles Bibliográficos
Autores principales: Liu, Hongxia, Liu, Ningning, Zhao, Yali, Zhu, Xiaoshan, Wang, Changsong, Liu, Qinqin, Gao, Chunfang, Zhao, Xusheng, Li, Juntang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874452/
https://www.ncbi.nlm.nih.gov/pubmed/31689236
http://dx.doi.org/10.18632/aging.102410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874452/
https://www.ncbi.nlm.nih.gov/pubmed/31689236
http://dx.doi.org/10.18632/aging.102410

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