Loss of FoxA2 accelerates neoplastic changes in the intrahepatic bile duct partly via the MAPK signaling pathway

Background: Intrahepatic cholangiocarcinoma (ICC) is characterized by a highly aggressive nature and a dismal outcome. FOXA2 is an archetypal transcription factor involved in cholangiocyte proliferation. Results: FOXA2 expression was negatively correlated with tumor stage (p = 0.024). Univariate and...

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Detalles Bibliográficos
Autores principales: Shen, Junyi, Zhou, Yongjie, Zhang, Xiaoyun, Peng, Wei, Peng, Chihan, Zhou, Qiang, Li, Chuan, Wen, Tianfu, Shi, Yujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874455/
https://www.ncbi.nlm.nih.gov/pubmed/31689237
http://dx.doi.org/10.18632/aging.102332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874455/
https://www.ncbi.nlm.nih.gov/pubmed/31689237
http://dx.doi.org/10.18632/aging.102332

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