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Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1

Pathophysiological states cause misfolded protein accumulation in the endoplasmic reticulum (ER). Then, ER stress and the unfolded protein response (UPR) are activated. Targeting ER stress may enhance the adaptive UPR and then protect the cell against pathogenic environments. In the present study, w...

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Detalles Bibliográficos
Autores principales: Cheng, Fong-Yu, Lee, Yu-Hsuan, Hsu, Yung-Ho, Chiu, I-Jen, Chiu, Yu-Jhe, Lin, Yuh-Feng, Chiu, Hui-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874456/
https://www.ncbi.nlm.nih.gov/pubmed/31714893
http://dx.doi.org/10.18632/aging.102437