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Long non-coding RNA PVT1 encapsulated in bone marrow mesenchymal stem cell-derived exosomes promotes osteosarcoma growth and metastasis by stabilizing ERG and sponging miR-183-5p

Exosomes secreted by bone marrow mesenchymal stem cells (BMSCs) promote osteosarcoma cell proliferation and migration, while the underlying mechanism remains unknown. Since the long non-coding RNA PVT1 has been reported to be upregulated in osteosarcoma cells and contributes to its growth and metast...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Qin, Pan, Zhang, Da, Cui, Xichun, Gao, Jing, Yu, Zhenzhu, Chai, Yuting, Wang, Jiaxiang, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874467/
https://www.ncbi.nlm.nih.gov/pubmed/31699956
http://dx.doi.org/10.18632/aging.102406