An epigenetic screening determines BET proteins as targets to suppress self-renewal and tumorigenicity in canine mammary cancer cells

Targeting self-renewal and tumorigenicity has been proposed as a potential strategy against cancer stem cells (CSCs). Epigenetic proteins are key modulators of gene expression and cancer development contributing to regulation and maintenance of self-renewal and tumorigenicity. Here, we have screened...

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Detalles Bibliográficos
Autores principales: Xavier, Pedro L. P., Cordeiro, Yonara G., Alexandre, Pâmela A., Pires, Pedro R. L., Saranholi, Bruno H., Silva, Edson R., Müller, Susanne, Fukumasu, Heidge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874531/
https://www.ncbi.nlm.nih.gov/pubmed/31758045
http://dx.doi.org/10.1038/s41598-019-53915-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874531/
https://www.ncbi.nlm.nih.gov/pubmed/31758045
http://dx.doi.org/10.1038/s41598-019-53915-7

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