New Alzheimer’s disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid β oligomers

Oligomers of intracellular amyloid β protein (Aβ) are strongly cytotoxic and play crucial roles in synaptic transmission and cognitive function in Alzheimer’s disease (AD). However, there is currently no AD model mouse in which to specifically analyze the function of Aβ oligomers only. We have now d...

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Detalles Bibliográficos
Autores principales: Ochiishi, Tomoyo, Kaku, Masami, Kiyosue, Kazuyuki, Doi, Motomichi, Urabe, Takao, Hattori, Nobutaka, Shimura, Hideki, Ebihara, Tatsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874556/
https://www.ncbi.nlm.nih.gov/pubmed/31757975
http://dx.doi.org/10.1038/s41598-019-53415-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874556/
https://www.ncbi.nlm.nih.gov/pubmed/31757975
http://dx.doi.org/10.1038/s41598-019-53415-8

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