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Engineering dual-glycan responsive expression systems for tunable production of heterologous proteins in Bacteroides thetaiotaomicron

Genetically engineering intestinal bacteria, such as Bacteroides thetaiotaomicron (B. theta), holds potential for creating new classes of biological devices, such as diagnostics or therapeutic delivery systems. Here, we have developed a series of B. theta strains that produce functional transgenic e...

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Detalles Bibliográficos
Autores principales: Jones, Darryl R., Smith, Marshall B., McLean, Richard, Grondin, Julie M., Amundsen, Carolyn R., Inglis, G. Douglas, Selinger, Brent, Abbott, D. Wade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874557/
https://www.ncbi.nlm.nih.gov/pubmed/31758019
http://dx.doi.org/10.1038/s41598-019-53726-w