FGF Signalling in the Self-Renewal of Colon Cancer Organoids

The progression of colorectal cancer (CRC) is supposedly driven by cancer stem cells (CSC) which are able to self-renew and simultaneously fuel bulk tumour mass with highly proliferative and differentiated tumour cells. However, the CSC-phenotype in CRC is unstable and dependent on environmental cue...

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Detalles Bibliográficos
Autores principales: Otte, Jörg, Dizdar, Levent, Behrens, Bianca, Goering, Wolfgang, Knoefel, Wolfram T., Wruck, Wasco, Stoecklein, Nikolas H., Adjaye, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874569/
https://www.ncbi.nlm.nih.gov/pubmed/31758153
http://dx.doi.org/10.1038/s41598-019-53907-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874569/
https://www.ncbi.nlm.nih.gov/pubmed/31758153
http://dx.doi.org/10.1038/s41598-019-53907-7

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