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FGF Signalling in the Self-Renewal of Colon Cancer Organoids

The progression of colorectal cancer (CRC) is supposedly driven by cancer stem cells (CSC) which are able to self-renew and simultaneously fuel bulk tumour mass with highly proliferative and differentiated tumour cells. However, the CSC-phenotype in CRC is unstable and dependent on environmental cue...

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Detalles Bibliográficos
Autores principales:	Otte, Jörg, Dizdar, Levent, Behrens, Bianca, Goering, Wolfgang, Knoefel, Wolfram T., Wruck, Wasco, Stoecklein, Nikolas H., Adjaye, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874569/ https://www.ncbi.nlm.nih.gov/pubmed/31758153 http://dx.doi.org/10.1038/s41598-019-53907-7

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