The MUC5B mucin polymer is dominated by repeating structural motifs and its topology is regulated by calcium and pH

The polymeric mucin MUC5B provides the structural and functional framework of respiratory mucus, conferring both viscoelastic and antimicrobial properties onto this vital protective barrier. Whilst it is established that MUC5B forms disulfide-linked linear polymers, how this relates to their packagi...

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Detalles Bibliográficos
Autores principales: Hughes, Gareth W., Ridley, Caroline, Collins, Richard, Roseman, Alan, Ford, Robert, Thornton, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874590/
https://www.ncbi.nlm.nih.gov/pubmed/31758042
http://dx.doi.org/10.1038/s41598-019-53768-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874590/
https://www.ncbi.nlm.nih.gov/pubmed/31758042
http://dx.doi.org/10.1038/s41598-019-53768-0

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