A new model isolates glioblastoma clonal interactions and reveals unexpected modes for regulating motility, proliferation, and drug resistance

Tumor clonal heterogeneity drives treatment resistance. But robust models are lacking that permit eavesdropping on the basic interaction network of tumor clones. We developed an in vitro, functional model of clonal cooperation using U87MG glioblastoma cells, which isolates fundamental clonal interac...

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Detalles Bibliográficos
Autores principales: Davis, Justin B, Krishna, Sreshta S, Abi Jomaa, Ryan, Duong, Cindy T., Espina, Virginia, Liotta, Lance A, Mueller, Claudius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874607/
https://www.ncbi.nlm.nih.gov/pubmed/31758030
http://dx.doi.org/10.1038/s41598-019-53850-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874607/
https://www.ncbi.nlm.nih.gov/pubmed/31758030
http://dx.doi.org/10.1038/s41598-019-53850-7

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