Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson’s disease

Mitochondrial degeneration is considered one of the major causes of Parkinson’s disease (PD). Improved mitochondrial functions are expected to be a promising therapeutic strategy for PD. In this study, we introduced a light-driven proton transporter, Delta-rhodopsin (dR), to Drosophila mitochondria,...

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Detalles Bibliográficos
Autores principales: Imai, Yuzuru, Inoshita, Tsuyoshi, Meng, Hongrui, Shiba-Fukushima, Kahori, Hara, Kiyotaka Y., Sawamura, Naoya, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874642/
https://www.ncbi.nlm.nih.gov/pubmed/31799427
http://dx.doi.org/10.1038/s42003-019-0674-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874642/
https://www.ncbi.nlm.nih.gov/pubmed/31799427
http://dx.doi.org/10.1038/s42003-019-0674-1

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