Cargando…

Lowering the culture temperature corrects collagen abnormalities caused by HSP47 gene knockout

Heat shock protein 47 (HSP47) is an endoplasmic reticulum (ER)-resident molecular chaperone that specifically recognizes triple helical portions of procollagens. The chaperone function of HSP47 is indispensable in mammals, and hsp47-null mice show an embryonic lethal phenotype accompanied by severe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fujii, Kazunori K., Taga, Yuki, Sakai, Takayuki, Ito, Shinya, Hattori, Shunji, Nagata, Kazuhiro, Koide, Takaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874656/ https://www.ncbi.nlm.nih.gov/pubmed/31758055 http://dx.doi.org/10.1038/s41598-019-53962-0

Ejemplares similares

The Thermal Stability of the Collagen Triple Helix Is Tuned According to the Environmental Temperature
por: Fujii, Kazunori K., et al.
Publicado: (2022)

NMR and Mutational Identification of the Collagen-Binding Site of the Chaperone Hsp47
por: Yagi-Utsumi, Maho, et al.
Publicado: (2012)

Embryonic Lethality of Molecular Chaperone Hsp47 Knockout Mice Is Associated with Defects in Collagen Biosynthesis
por: Nagai, Naoko, et al.
Publicado: (2000)

A BRET-based assay reveals collagen–Hsp47 interaction dynamics in the endoplasmic reticulum and small-molecule inhibition of this interaction
por: Ito, Shinya, et al.
Publicado: (2019)

In-depth correlation analysis demonstrates that 4-hydroxyproline at the Yaa position of Gly-Xaa-Yaa repeats dominantly stabilizes collagen triple helix
por: Taga, Yuki, et al.
Publicado: (2021)

HSP47 levels determine the degree of body adiposity
por: Shin, Jihoon, et al.
Publicado: (2023)

Identification of HSP47 Binding Site on Native Collagen and Its Implications for the Development of HSP47 Inhibitors
por: Cai, Haiyan, et al.
Publicado: (2021)

Hsp47 promotes cancer metastasis by enhancing collagen-dependent cancer cell-platelet interaction
por: Xiong, Gaofeng, et al.
Publicado: (2020)

Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart
por: Khalil, Hadi, et al.
Publicado: (2019)

Collagen’s primary structure determines collagen:HSP47 complex stoichiometry
por: Abraham, Elena T., et al.
Publicado: (2021)

Photoactivatable Hsp47: A Tool to Regulate Collagen Secretion and Assembly
por: Khan, Essak S., et al.
Publicado: (2019)

The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and hemostasis
por: Sasikumar, P., et al.
Publicado: (2018)

Retraction: Photoactivatable Hsp47: A Tool to Regulate Collagen Secretion and Assembly
por: Khan, Essak S., et al.
Publicado: (2023)

High serum concentrations of autoantibodies to HSP47 in nonspecific interstitial pneumonia compared with idiopathic pulmonary fibrosis
por: Kakugawa, Tomoyuki, et al.
Publicado: (2008)

Intracellular interaction of collagen-specific stress protein HSP47 with newly synthesized procollagen
Publicado: (1996)

Preservation of collagen in the soft tissues of frozen mammoths
por: Hattori, Shunji, et al.
Publicado: (2021)

Exogenous supply of Hsp47 triggers fibrillar collagen deposition in skin cell cultures in vitro
por: Khan, Essak S., et al.
Publicado: (2020)

Expression of the collagen-related heat shock protein HSP47 in fibroblasts treated with hyperthermia or photodynamic therapy.
por: Verrico, A. K., et al.
Publicado: (1997)

The Collagen Chaperone HSP47 Is a New Interactor of APP that Affects the Levels of Extracellular Beta-Amyloid Peptides
por: Bianchi, Federico T., et al.
Publicado: (2011)

Aberrant binding of mutant HSP47 affects posttranslational modification of type I collagen and leads to osteogenesis imperfecta
por: Syx, Delfien, et al.
Publicado: (2021)

The dipeptide prolyl-hydroxyproline promotes cellular homeostasis and lamellipodia-driven motility via active β1-integrin in adult tendon cells
por: Ide, Kentaro, et al.
Publicado: (2021)

Functional Role of HSP47 in the Periodontal Ligament Subjected to Occlusal Overload in Mice
por: Mimura, Hiroaki, et al.
Publicado: (2016)

Hsp47 Inhibitor Col003 Attenuates Collagen-Induced Platelet Activation and Cerebral Ischemic–Reperfusion Injury in Rats
por: Wu, Shuang, et al.
Publicado: (2022)

Immunoexpression of α2-integrin and Hsp47 in hereditary gingival fibromatosis and gingival fibromatosis-associated dental abnormalities
por: Vieira-Júnior, João R., et al.
Publicado: (2013)

Long-term intake of ginger protease-degraded collagen hydrolysate reduces blood lipid levels and adipocyte size in mice
por: Tometsuka, Chisa, et al.
Publicado: (2021)

Targeting HSP47 and HSP70: promising therapeutic approaches in liver fibrosis management
por: Abd El-Fattah, Eslam E., et al.
Publicado: (2022)

MiR-29/Hsp47 in ECM network
por: Xu, Ren
Publicado: (2015)

HSP47: A Therapeutic Target in Pulmonary Fibrosis
por: Sakamoto, Noriho, et al.
Publicado: (2023)

N(ω)-(Carboxymethyl)arginine Is One of the Dominant Advanced Glycation End Products in Glycated Collagens and Mouse Tissues
por: Kinoshita, Sho, et al.
Publicado: (2019)

Collagen molecular phenotypic switch between non-neoplastic and neoplastic canine mammary tissues
por: Terajima, Masahiko, et al.
Publicado: (2021)

Comprehensive Behavioral Analysis of Cluster of Differentiation 47 Knockout Mice
por: Koshimizu, Hisatsugu, et al.
Publicado: (2014)

Antisense oligonucleotide inhibition of Heat Shock Protein (HSP) 47 improves bleomycin-induced pulmonary fibrosis in rats
por: Hagiwara, Satoshi, et al.
Publicado: (2007)

Cyclophilin B control of lysine post-translational modifications of skin type I collagen
por: Terajima, Masahiko, et al.
Publicado: (2019)

Ancestry & molecular evolutionary analyses of heat shock protein 47 kDa (HSP47/SERPINH1)
por: Kumar, Abhishek, et al.
Publicado: (2017)

Collagen‐Specific HSP47 (+) Myofibroblasts and CD163 (+) Macrophages Identify Profibrotic Phenotypes in Deceased Hearts With SARS‐CoV‐2 Infections
por: Puzyrenko, Andrii, et al.
Publicado: (2023)

Involvement of the stress protein HSP47 in procollagen processing in the endoplasmic reticulum
Publicado: (1992)

Expression of HSP47 in Usual Interstitial Pneumonia and Nonspecific Interstitial Pneumonia
por: Kakugawa, Tomoyuki, et al.
Publicado: (2005)

Expression of Collagen (Types I, III, and V), HSP47, MMP-2, and TIMP-1 in Retrobulbar Adipose Tissue of Patients with Thyroid-Associated Orbitopathy
por: Luo, Hongyang, et al.
Publicado: (2020)

Dietary collagen peptides alleviate exercise-induced muscle soreness in healthy middle-aged males: a randomized double-blinded crossover clinical trial
por: Kuwaba, Kumiko, et al.
Publicado: (2023)

Identification of a highly stable bioactive 3-hydroxyproline-containing tripeptide in human blood after collagen hydrolysate ingestion
por: Taga, Yuki, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7cr9p7ugf4nq9ik0i6lv9e9bf4