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Lupus-like Disease in FcγRIIB(−/−) Mice Induces Osteopenia

Osteoporotic fracture is a major cause of morbidity in patients with systemic lupus erythematosus (SLE). Mice lacking Fc gamma receptor IIb (FcγRIIB) spontaneously develop lupus-like disease or SLE at 6-month-old. The aim of this study was to investigate whether FcγRIIB deletion induces osteopenia....

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Detalles Bibliográficos
Autores principales: Visitchanakun, Peerapat, Saiworn, Worasit, Jongwattanapisan, Prapaporn, Leelahavanichkul, Asada, Pisitkun, Prapaporn, Lotinun, Sutada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874658/
https://www.ncbi.nlm.nih.gov/pubmed/31758072
http://dx.doi.org/10.1038/s41598-019-53963-z