Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease

Alpha-synuclein (aSyn) is the main component of Lewy bodies, the histopathological marker in Parkinson’s disease (PD), and point mutations and multiplications of the aSyn coding SNCA gene correlate with early onset PD. Therefore, various transgenic mouse models overexpressing native or point-mutated...

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Detalles Bibliográficos
Autores principales: Kilpeläinen, Tommi, Julku, Ulrika H., Svarcbahs, Reinis, Myöhänen, Timo T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874660/
https://www.ncbi.nlm.nih.gov/pubmed/31758049
http://dx.doi.org/10.1038/s41598-019-54034-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874660/
https://www.ncbi.nlm.nih.gov/pubmed/31758049
http://dx.doi.org/10.1038/s41598-019-54034-z

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