Highly thermostable carboxylic acid reductases generated by ancestral sequence reconstruction

Carboxylic acid reductases (CARs) are biocatalysts of industrial importance. Their properties, especially their poor stability, render them sub-optimal for use in a bioindustrial pipeline. Here, we employed ancestral sequence reconstruction (ASR) – a burgeoning engineering tool that can identify sta...

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Detalles Bibliográficos
Autores principales: Thomas, Adam, Cutlan, Rhys, Finnigan, William, van der Giezen, Mark, Harmer, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874671/
https://www.ncbi.nlm.nih.gov/pubmed/31799431
http://dx.doi.org/10.1038/s42003-019-0677-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874671/
https://www.ncbi.nlm.nih.gov/pubmed/31799431
http://dx.doi.org/10.1038/s42003-019-0677-y

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