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Highly thermostable carboxylic acid reductases generated by ancestral sequence reconstruction
Carboxylic acid reductases (CARs) are biocatalysts of industrial importance. Their properties, especially their poor stability, render them sub-optimal for use in a bioindustrial pipeline. Here, we employed ancestral sequence reconstruction (ASR) – a burgeoning engineering tool that can identify sta...
Autores principales: | Thomas, Adam, Cutlan, Rhys, Finnigan, William, van der Giezen, Mark, Harmer, Nicholas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874671/ https://www.ncbi.nlm.nih.gov/pubmed/31799431 http://dx.doi.org/10.1038/s42003-019-0677-y |
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