Transcription modulation by CDK9 regulates inflammatory genes and RIPK3-MLKL-mediated necroptosis in periodontitis progression

Cyclin-dependent kinase 9 (CDK9), one crucial molecule in promoting the transition from transcription pausing to elongation, is a critical modulator of cell survival and death. However, the pathological function of CDK9 in bacterial inflammatory diseases has never been explored. CDK9 inhibition or k...

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Detalles Bibliográficos
Autores principales: Li, Jiao, Shi, Jiahong, Pan, Yue, Zhao, Yunhe, Yan, Fuhua, Li, Houxuan, Lei, Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874675/
https://www.ncbi.nlm.nih.gov/pubmed/31758083
http://dx.doi.org/10.1038/s41598-019-53910-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874675/
https://www.ncbi.nlm.nih.gov/pubmed/31758083
http://dx.doi.org/10.1038/s41598-019-53910-y

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