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ELFN2 is a postsynaptic cell adhesion molecule with essential roles in controlling group III mGluRs in the brain and neuropsychiatric behavior

The functional characterization of the GPCR interactome has predominantly focused on intracellular binding partners; however, the recent emergence of trans-synaptic GPCR complexes represents an additional dimension to GPCR function that has previously been unaccounted for in drug discovery. Here, we...

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Detalles Bibliográficos
Autores principales: Dunn, Henry A., Zucca, Stefano, Dao, Maria, Orlandi, Cesare, Martemyanov, Kirill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874751/
https://www.ncbi.nlm.nih.gov/pubmed/31485013
http://dx.doi.org/10.1038/s41380-019-0512-3