Elevated glucose acts directly on osteocytes to increase sclerostin expression in diabetes

Bone quality in diabetic patients is compromised, leading to weaker bones and increased fracture risk. However, the mechanism by which this occurs in diabetic bone remains to be fully elucidated. We hypothesized that elevated glucose and glucose variation would affect the function of osteocytes, ess...

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Detalles Bibliográficos
Autores principales: Pacicca, Donna M., Brown, Tammy, Watkins, Dara, Kover, Karen, Yan, Yun, Prideaux, Matthew, Bonewald, Lynda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874765/
https://www.ncbi.nlm.nih.gov/pubmed/31757981
http://dx.doi.org/10.1038/s41598-019-52224-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874765/
https://www.ncbi.nlm.nih.gov/pubmed/31757981
http://dx.doi.org/10.1038/s41598-019-52224-3

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