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LKB1/AMPK Pathway and Drug Response in Cancer: A Therapeutic Perspective

Inactivating mutations of the tumor suppressor gene Liver Kinase B1 (LKB1) are frequently detected in non-small-cell lung cancer (NSCLC) and cervical carcinoma. Moreover, LKB1 expression is epigenetically regulated in several tumor types. LKB1 has an established function in the control of cell metab...

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Detalles Bibliográficos
Autores principales: Ciccarese, Francesco, Zulato, Elisabetta, Indraccolo, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874879/
https://www.ncbi.nlm.nih.gov/pubmed/31781355
http://dx.doi.org/10.1155/2019/8730816