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Lyophilized B. subtilis ZB183 Spores: 90-Day Repeat Dose Oral (Gavage) Toxicity Study in Wistar Rats

A 90-day repeated-dose oral toxicological evaluation was conducted according to GLP and OECD guidelines on lyophilized spores of the novel genetically modified strain B. subtilis ZB183. Lyophilized spores at doses of 10(9), 10(10), and 10(11) CFU/kg body weight/day were administered by oral gavage t...

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Detalles Bibliográficos
Autores principales: Appala Naidu, B., Kannan, Kamala, Santhosh Kumar, D. P., Oliver, John W. K., Abbott, Zachary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875028/
https://www.ncbi.nlm.nih.gov/pubmed/31781202
http://dx.doi.org/10.1155/2019/3042108