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Regulatory Effect of 1,25(OH)2D3 on TGF-β1 and miR-130b Expression in Streptozotocin-Induced Diabetic Nephropathy in Rats

OBJECTIVE: To investigate the role of microRNA-130b in 1,25(OH)2D3 mediated improvement of renal fibrosis via transforming growth factor-beta 1 in a rat model of diabetic nephropathy (DN). METHODS: DN was induced in 30 rats by intraperitoneal injection of streptozotocin. These rats were randomly all...

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Detalles Bibliográficos
Autores principales: Liu, Yuetong, Yang, Ye, Wang, Qin, Kahaer, Apaer, Zhang, Jiyun, Liao, Jing, Abudureyimu, Mairemugu, Yahefu, Reyila, Qi, Jing, Zhao, Lei, Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875179/
https://www.ncbi.nlm.nih.gov/pubmed/31781203
http://dx.doi.org/10.1155/2019/1231346