miR-200a Attenuated Doxorubicin-Induced Cardiotoxicity through Upregulation of Nrf2 in Mice

Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) was closely involved in doxorubicin- (DOX-) induced cardiotoxicity. MicroRNA-200a (miR-200a) could target Keap1 mRNA and promote degradation of Keap1 mRNA, resulting in Nrf2 activation. However, the role of miR-200a in DOX-related cardiotoxicity rem...

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Detalles Bibliográficos
Autores principales: Hu, Xiaoping, Liu, Huagang, Wang, Zhiwei, Hu, Zhipeng, Li, Luocheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875222/
https://www.ncbi.nlm.nih.gov/pubmed/31781322
http://dx.doi.org/10.1155/2019/1512326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875222/
https://www.ncbi.nlm.nih.gov/pubmed/31781322
http://dx.doi.org/10.1155/2019/1512326

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