Targeting L-Lactate Metabolism to Overcome Resistance to Immune Therapy of Melanoma and Other Tumor Entities

Although immunotherapy plays a significant role in tumor therapy, its efficacy is impaired by an immunosuppressive tumor microenvironment. A molecule that contributes to the protumor microenvironment is the metabolic product lactate. Lactate is produced in large amounts by cancer cells in response t...

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Detalles Bibliográficos
Autores principales: Feichtinger, René G., Lang, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875281/
https://www.ncbi.nlm.nih.gov/pubmed/31781212
http://dx.doi.org/10.1155/2019/2084195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875281/
https://www.ncbi.nlm.nih.gov/pubmed/31781212
http://dx.doi.org/10.1155/2019/2084195

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