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Computational Analysis of nsSNPs of ADA Gene in Severe Combined Immunodeficiency Using Molecular Modeling and Dynamics Simulation

Severe combined immunodeficiency (SCID) is the most severe form of primary immunodeficiency (PID), characterized by fatal opportunistic infections. The ADA gene encodes adenosine deaminase, an enzyme that catalyzes the irreversible deamination of adenosine and deoxyadenosine in the catabolic pathway...

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Detalles Bibliográficos
Autores principales: Essadssi, Soukaina, Krami, Al Mehdi, Elkhattabi, Lamiae, Elkarhat, Zouhair, Amalou, Ghita, Abdelghaffar, Houria, Rouba, Hassan, Barakat, Abdelhamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875294/
https://www.ncbi.nlm.nih.gov/pubmed/31781678
http://dx.doi.org/10.1155/2019/5902391