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miR-23b Negatively Regulates Sepsis-Induced Inflammatory Responses by Targeting ADAM10 in Human THP-1 Monocytes

BACKGROUND: Previous studies have demonstrated pivotal roles of disintegrin and metalloproteinase 10 (ADAM10) in the pathogenesis of sepsis. MicroRNA- (miR-) 23b has emerged as an anti-inflammatory factor that prevents multiple autoimmune diseases. However, the underlying mechanisms of miR-23b in th...

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Detalles Bibliográficos
Autores principales: Zhang, Wenying, Lu, Furong, Xie, Yuliu, Lin, Yao, Zhao, Tian, Tao, Shoubao, Lai, Zhipeng, Wei, Ning, Yang, Ruoxuan, Shao, Yiming, He, Junbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875296/
https://www.ncbi.nlm.nih.gov/pubmed/31780861
http://dx.doi.org/10.1155/2019/5306541