Inhibition of cAMP/PKA Pathway Protects Optic Nerve Head Astrocytes against Oxidative Stress by Akt/Bax Phosphorylation-Mediated Mfn1/2 Oligomerization

Glaucoma is characterized by a progressive optic nerve degeneration and retinal ganglion cell loss, but the underlying biological basis for the accompanying neurodegeneration is not known. Accumulating evidence indicates that structural and functional abnormalities of astrocytes within the optic ner...

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Detalles Bibliográficos
Autores principales: Ju, Won-Kyu, Shim, Myoung Sup, Kim, Keun-Young, Park, Tae Lim, Ahn, Sangphil, Edwards, Genea, Weinreb, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875302/
https://www.ncbi.nlm.nih.gov/pubmed/31781352
http://dx.doi.org/10.1155/2019/8060962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875302/
https://www.ncbi.nlm.nih.gov/pubmed/31781352
http://dx.doi.org/10.1155/2019/8060962

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