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Characterizing the invasion of different breast cancer cell lines with distinct E-cadherin status in 3D using a microfluidic system
E-cadherin is a cell-cell adhesion protein that plays a prominent role in cancer invasion. Inactivation of E-cadherin in breast cancer can arise from gene promoter hypermethylation or genetic mutation. Depending on their E-cadherin status, breast cancer cells adopt different morphologies with distin...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875428/ https://www.ncbi.nlm.nih.gov/pubmed/31760501 http://dx.doi.org/10.1007/s10544-019-0450-5 |