Treatment with Methotrexate and Intravenous Cyclophosphamide Pulse Therapy Regulates the P-gp(+)CD4(+) Cell-related Pathogenesis in a Representative Patient with Refractory Proliferative Lupus Nephritis

Diffuse proliferative lupus nephritis (DPLN) is a serious organ complication. Drug resistance correlates with P-glycoprotein (P-gp) expression on activated lymphocytes. We encountered a refractory DPLN patient with expansion of peripheral CD69/CXCR3-co-expressing P-gp(+)CD4(+) cells producing IL-2 a...

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Detalles Bibliográficos
Autores principales: Tsujimura, Shizuyo, Tanaka, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875445/
https://www.ncbi.nlm.nih.gov/pubmed/31685786
http://dx.doi.org/10.2169/internalmedicine.2589-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875445/
https://www.ncbi.nlm.nih.gov/pubmed/31685786
http://dx.doi.org/10.2169/internalmedicine.2589-18

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