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Friend or foe—IDH1 mutations in glioma 10 years on

The identification of recurrent point mutations in the isocitrate dehydrogenase 1 (IDH1) gene, albeit in only a small percentage of glioblastomas a decade ago, has transformed our understanding of glioma biology, genomics and metabolism. More than 1000 scientific papers have been published since, pr...

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Detalles Bibliográficos
Autor principal: Huang, L Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875900/
https://www.ncbi.nlm.nih.gov/pubmed/31504231
http://dx.doi.org/10.1093/carcin/bgz134