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The Oncogene PIM1 Contributes to Cellular Senescence by Phosphorylating Staphylococcal Nuclease Domain-Containing Protein 1 (SND1)

BACKGROUND: The oncogene PIM1, encoding a constitutively active serine/threonine protein kinase, is involved in the regulation of cell proliferation, survival, differentiation, and apoptosis. There is a growing body of literature on the role of PIM1-mediated cellular senescence, but the precise mech...

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Detalles Bibliográficos
Autores principales: Wu, Wu, Yu, Aiqing, Chen, Keyu, Lu, Peilin, Yang, Jianming, Liu, Kun, Mao, Zebin, Yao, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876065/
https://www.ncbi.nlm.nih.gov/pubmed/31860636
http://dx.doi.org/10.12659/MSM.917867