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The Oncogene PIM1 Contributes to Cellular Senescence by Phosphorylating Staphylococcal Nuclease Domain-Containing Protein 1 (SND1)
BACKGROUND: The oncogene PIM1, encoding a constitutively active serine/threonine protein kinase, is involved in the regulation of cell proliferation, survival, differentiation, and apoptosis. There is a growing body of literature on the role of PIM1-mediated cellular senescence, but the precise mech...
Autores principales: | Wu, Wu, Yu, Aiqing, Chen, Keyu, Lu, Peilin, Yang, Jianming, Liu, Kun, Mao, Zebin, Yao, Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876065/ https://www.ncbi.nlm.nih.gov/pubmed/31860636 http://dx.doi.org/10.12659/MSM.917867 |
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